Clearance of I 131 injected intralesionally in patients with psoriasis.

Vascular changes undoubtedly play a significant role in the pathogenesis of psoriasis. The present study concerns the local hemodynamics of psoriatic plaques measured by skin clearance of radioactive substances. This method gives a rough measure of local vascular dynamics (1—7), and, despite any shortcomings, probably supplies a more realistic picture than does use of colorimetry or plethysmography (3).